High-current stimulator

The unique high-current device is produced only in one-channel design. The mutual characteristics of the device are the identical stimulus impulse and performance parameters. They are without isolation, operating from the electrical system.

The MCU controlling unit is built into one rack with the one- or two-channel stimulators and supplied separately in case of four-channel stimulator.

Specification

High-current stimulator
Max. output performance	50 W
Impulse rise/fall	10μsec/100V
Voltage output
Max output voltage	±10V, ±100V
Max. current load	±500mA
Output protection	Short-circuit protected
Current output
Max. output current	±10mA, ±100mA
Max output voltage	±100V
Output protection	Short-circuit protected
Output connector	Banana plug (4mm)
Input connector	9-pole D-SUB (Cannon)
Power supply	110V or 220V, 50/60 Hz

Available models

EXP-ST-P1 One-channel high-current stimulator with built-in MCU controlling unit

References

Year	Author	Title	Source
1996	Pogátsa G, Koltai ZsM, Pósa I, Kocsis E, Papp JG.	Effect of hypoglycemic sulphonylureas on vagal functions	Clin exp Cardiol Vol 1 No 1 Summer 1996
1998	Szilvássy Z, Ferdinandy P, Cluff CW, Elliott GT.	Antiischemic effect of monophosphoryl lipid A in conscious rabbits with hypercholesterolemia and atherosclerosis	J Cardiovasc Pharmacol. 1998 Aug;32(2):206-12.
2001	Stavrou BM, Beck C, Flores NA.	Changes in extracellular pH and myocardial ischaemia alter the cardiac effects of diadenosine tetraphosphate and pentaphosphate	Br J Pharmacol. 2001 Oct;134(3):639-47.
2001	Stavrou BM, Sheridan DJ, Flores NA.	Contribution of nitric oxide and prostanoids to the cardiac electrophysiological and coronary vasomotor effects of diadenosine polyphosphates	J Pharmacol Exp Ther. 2001 Aug;298(2):531-8.
2001	Stavrou BM, Lawrence C, Blackburn GM, Cohen T, Sheridan DJ, Flores NA.	Coronary vasomotor and cardiac electrophysiologic effects of diadenosine polyphosphates and nonhydrolyzable analogs in the guinea pig	J Cardiovasc Pharmacol. 2001 May;37(5):571-84.
2001	Kovács A, Gyönös I, Magyar J, Bányász T, Nánási PP, Spedding M, Szénási G.	Effects of EGIS-7229 (S 21407), a novel class III antiarrhythmic drug, on myocardial refractoriness to electrical stimulation in vivo and in vitro	J Cardiovasc Pharmacol. 2001 Jan;37(1):78-88.
2002	Klukovits A, Gáspár R, Sántha P, Jancsó G, Falkay G.	Functional and histochemical characterization of a uterine adrenergic denervation process in pregnant rats	Biol Reprod. 2002 Sep;67(3):1013-7.
2003	Rubovszky B, Szentmiklósi AJ, Márián T, Cseppento A, Gesztelyi R, Székely A, Fórizs F, Gáspár R, Trón L, Krasznai Z.	Comparative pharmacological studies on the A2 adenosine receptor agonist 5'-n-ethyl-carboxamidoadenosine and its F19 isotope labelled derivative	J Pharmacol Sci. 2003 Nov;93(3):356-63.
2003	Csonka C, Onody A, Csont T, Ferdinandy P.	Defibrillatory action of glibenclamide is independent from ATP-sensitive K+ channels and free radicals	J Cardiovasc Pharmacol. 2003 Jun;41(6):916-22.
2003	Mihályi A, Ducza E, Gáspár R, Falkay G.	Investigation of the role of the serotonergic activity of certain subtype-selective alpha1A antagonists in the relaxant effect on the pregnant rat uterus in vitro	Mol Hum Reprod. 2003 Aug;9(8):475-80.
2005	Benkó R, Undi S, Wolf M, Barthó L.	Effects of acute administration of and tachyphylaxis to alpha,beta-methylene ATP in the guinea-pig small intestine	Basic Clin Pharmacol Toxicol. 2005 Dec;97(6):369-73.
2005	Turchányi B, Tóth B, Rácz I, Vendégh Z, Furész J, Hamar J.	Ischemia reperfusion injury of the skeletal muscle after selective deafferentation	Physiol Res. 2005;54(1):25-32.
2006	Dworakowski R, Dworakowska D, Kocic I, Wirth T, Gruchała M, Kamiński M, Petrusewicz J, Yla-Herttuala S, Rynkiewicz A.	Cerivastatin and hypercholesterolemia reduce apoptosis of cardiomyocytes in guinea pig papillary muscle subjected to hypoxia/reoxygenation	Pharmacol Rep. 2006 May-Jun;58(3):420-6.
2006	Raghu KG.	Effect of melittin on electrically driven action potential of guinea pig papillary muscle	Journal of Cell and Tissue Research Vol. 6 (2) 749-752 (2006)
2006	Karsai D, Zsuga J, Juhász B, Dér P, Szentmiklósi AJ, Tósaki A, Gesztelyi R.	Effect of nucleoside transport blockade on the interstitial adenosine level characterized by a novel method in guinea pig atria	J Cardiovasc Pharmacol. 2006 Jan;47(1):103-9.
2009	Stratos I.	Einfluss von Granulozyten-Kolonie stimulierendem Faktor auf die tarmatsierte periphere Skelettmuskulatur der Ratte	Aus dem Institut für Experimentelle Chirurgie der Medizinischen Fakultät, der Universität Rostock, PhD
2009	Prorok J, Kovács PP, Kristóf AA, Nagy N, Tombácz D, Tóth JS, Ordög B, Jost N, Virág L, Papp JG, Varró A, Tóth A, Boldogkoi Z.	Herpesvirus-mediated delivery of a genetically encoded fluorescent Ca(2+) sensor to canine cardiomyocytes	J Biomed Biotechnol. 2009;2009:361795. doi: 10.1155/2009/361795. Epub 2009 Jul 14.
2009	Sprossmann F, Pankert P, Sausbier U, Wirth A, Zhou XB, Madlung J, Zhao H, Bucurenciu I, Jakob A, Lamkemeyer T, Neuhuber W, Offermanns S, Shipston MJ, Korth M, Nordheim A, Ruth P, Sausbier M.	Inducible knockout mutagenesis reveals compensatory mechanisms elicited by constitutive BK channel deﬁciency in overactive murine bladder	FEBS J. 2009 Mar;276(6):1680-97. doi: 10.1111/j.1742-4658.2009.06900.x. Epub 2008 Feb 12.
2010	Radomirov R, Negrev N, Itzev DE, Stavreva G.	Activation-dependent descending reflex evacuation of anal canal in a rat model	Arch Ital Biol. 2010 Dec;148(4):377-88. doi: 10.4449/aib.v148i4.1200.
2010	Csonka D.	Investigation of pregnancy induced adrenergic denervation in the rat	University of Szeged, Faculty of Pharmacy, Department of Pharmacodynamics and Biopharmacy
2011	Kocic I, Dworakowska D, Dworakowski R, Petrusewicz J.	CGP 41251, a new potential anticancer drug, improves contractility of rat isolated cardiac muscle subjected to hypoxia	J Cardiovasc Pharmacol. 2001 Jun;37(6):734-41.
2012	Raducu Popescu I, Bild W, Ciobica A, Bild V.	Different modulatory effects of ammonium ions on angiotensin vascular actions in isolated rat aortic and renal arteries	Arch. Biol. Sci., Belgrade, 64 (2), 427-433, 2012
2013	Jost N, Nagy N, Corici C, Kohajda Z, Horváth A, Acsai K, Biliczki P, Levijoki J, Pollesello P, Koskelainen T, Otsomaa L, Tóth A, Papp JG, Varró A, Virág L.	ORM-10103, a novel specific inhibitor of the Na+/Ca2+ exchanger, decreases early and delayed afterdepolarizations in the canine heart	Br J Pharmacol. 2013 Oct;170(4):768-78. doi: 10.1111/bph.12228.
2014	Sarika Singh,Sharad Sharma, C. Nath, Srikant Kumar Rath, R. K. Singh, Smrati Bhadauria, Poonam Singh, R.k. Shukla, Manoj Barthwal, M Dikshit	Essential safety pharmacology and safety evaluation of bioactive fraction of Xylocarpus moluccensis an antidyslipidaemic agent	International journal of medical science and clinical Invention Volume 1 Issue 1 2014 page no. 24-47

Note: experiments were performed with different types of stimulators.

Media

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