Non-isolated stimulators

One-channel non-isolated stimulatorOne-channel non-isolated stimulator

The devices (EXP-ST-0X products) are produced in one-, two- and four-channel designs. The mutual characteristics of the devices are the identical stimulus impulse and performance parameters. They are without isolation, operating from the electrical system.

The MCU controlling unit is built into one rack with the one- or two-channel stimulators and supplied separately in case of four-channel stimulator.



Non-isolated stimulators  
Max. output performance 10 W/ch
Impulse rise/fall 10μsec/100V
Voltage output  
   Max output voltage ±10V, ±100V
   Max. current load ±100mA
   Output protection Short-circuit protected
Current output  
   Max. output current ±10mA, ±100mA
   Max output voltage ±100V
   Output protection Short-circuit protected
Output connector Banana plug (4mm)
Input connector 9-pole D-SUB (Cannon)
Power supply 110V or 220V, 50/60 Hz

Available models

EXP-ST-01 One-channel non-isolated stimulator with built-in MCU controlling unit

EXP-ST-02 Two-channel non-isolated stimulator with built-in MCU controlling unit

EXP-ST-04 Four-channel non-isolated stimulator with MCU controlling unit


 Year  Author  Title  Source
1996 Pogátsa G, Koltai ZsM, Pósa I, Kocsis E, Papp JG. Effect of hypoglycemic sulphonylureas on vagal functions Clin exp Cardiol Vol 1 No 1 Summer 1996
1998 Szilvássy Z, Ferdinandy P, Cluff CW, Elliott GT. Antiischemic effect of monophosphoryl lipid A in conscious rabbits with hypercholesterolemia and atherosclerosis J Cardiovasc Pharmacol. 1998 Aug;32(2):206-12.
2001 Stavrou BM, Beck C, Flores NA. Changes in extracellular pH and myocardial ischaemia alter the cardiac effects of diadenosine tetraphosphate and pentaphosphate Br J Pharmacol. 2001 Oct;134(3):639-47.
2001 Stavrou BM, Sheridan DJ, Flores NA. Contribution of nitric oxide and prostanoids to the cardiac electrophysiological and coronary vasomotor effects of diadenosine polyphosphates J Pharmacol Exp Ther. 2001 Aug;298(2):531-8.
2001 Stavrou BM, Lawrence C, Blackburn GM, Cohen T, Sheridan DJ, Flores NA. Coronary vasomotor and cardiac electrophysiologic effects of diadenosine polyphosphates and nonhydrolyzable analogs in the guinea pig J Cardiovasc Pharmacol. 2001 May;37(5):571-84.
2001 Kovács A, Gyönös I, Magyar J, Bányász T, Nánási PP, Spedding M, Szénási G. Effects of EGIS-7229 (S 21407), a novel class III antiarrhythmic drug, on myocardial refractoriness to electrical stimulation in vivo and in vitro J Cardiovasc Pharmacol. 2001 Jan;37(1):78-88.
2002 Klukovits A, Gáspár R, Sántha P, Jancsó G, Falkay G. Functional and histochemical characterization of a uterine adrenergic denervation process in pregnant rats Biol Reprod. 2002 Sep;67(3):1013-7.
2003 Rubovszky B, Szentmiklósi AJ, Márián T, Cseppento A, Gesztelyi R, Székely A, Fórizs F, Gáspár R, Trón L, Krasznai Z. Comparative pharmacological studies on the A2 adenosine receptor agonist 5'-n-ethyl-carboxamidoadenosine and its F19 isotope labelled derivative J Pharmacol Sci. 2003 Nov;93(3):356-63.
2003 Csonka C, Onody A, Csont T, Ferdinandy P. Defibrillatory action of glibenclamide is independent from ATP-sensitive K+ channels and free radicals J Cardiovasc Pharmacol. 2003 Jun;41(6):916-22.
2003 Mihályi A, Ducza E, Gáspár R, Falkay G. Investigation of the role of the serotonergic activity of certain subtype-selective alpha1A antagonists in the relaxant effect on the pregnant rat uterus in vitro Mol Hum Reprod. 2003 Aug;9(8):475-80.
2005 Benkó R, Undi S, Wolf M, Barthó L. Effects of acute administration of and tachyphylaxis to alpha,beta-methylene ATP in the guinea-pig small intestine Basic Clin Pharmacol Toxicol. 2005 Dec;97(6):369-73.
2005 Turchányi B, Tóth B, Rácz I, Vendégh Z, Furész J, Hamar J. Ischemia reperfusion injury of the skeletal muscle after selective deafferentation Physiol Res. 2005;54(1):25-32.
2006 Dworakowski R, Dworakowska D, Kocic I, Wirth T, Gruchała M, Kamiński M, Petrusewicz J, Yla-Herttuala S, Rynkiewicz A. Cerivastatin and hypercholesterolemia reduce apoptosis of cardiomyocytes in guinea pig papillary muscle subjected to hypoxia/reoxygenation Pharmacol Rep. 2006 May-Jun;58(3):420-6.
2006 Raghu KG. Effect of melittin on electrically driven action potential of guinea pig papillary muscle Journal of Cell and Tissue Research Vol. 6 (2) 749-752 (2006)
2006 Karsai D, Zsuga J, Juhász B, Dér P, Szentmiklósi AJ, Tósaki A, Gesztelyi R. Effect of nucleoside transport blockade on the interstitial adenosine level characterized by a novel method in guinea pig atria J Cardiovasc Pharmacol. 2006 Jan;47(1):103-9.
2009 Stratos I. Einfluss von Granulozyten-Kolonie stimulierendem Faktor auf die tarmatsierte periphere Skelettmuskulatur der Ratte Aus dem Institut für Experimentelle Chirurgie der Medizinischen Fakultät, der Universität Rostock, PhD
2009 Prorok J, Kovács PP, Kristóf AA, Nagy N, Tombácz D, Tóth JS, Ordög B, Jost N, Virág L, Papp JG, Varró A, Tóth A, Boldogkoi Z. Herpesvirus-mediated delivery of a genetically encoded fluorescent Ca(2+) sensor to canine cardiomyocytes J Biomed Biotechnol. 2009;2009:361795. doi: 10.1155/2009/361795. Epub 2009 Jul 14.
2009 Sprossmann F, Pankert P, Sausbier U, Wirth A, Zhou XB, Madlung J, Zhao H, Bucurenciu I, Jakob A, Lamkemeyer T, Neuhuber W, Offermanns S, Shipston MJ, Korth M, Nordheim A, Ruth P, Sausbier M. Inducible knockout mutagenesis reveals compensatory mechanisms elicited by constitutive BK channel deficiency in overactive murine bladder FEBS J. 2009 Mar;276(6):1680-97. doi: 10.1111/j.1742-4658.2009.06900.x. Epub 2008 Feb 12.
2010 Radomirov R, Negrev N, Itzev DE, Stavreva G. Activation-dependent descending reflex evacuation of anal canal in a rat model Arch Ital Biol. 2010 Dec;148(4):377-88. doi: 10.4449/aib.v148i4.1200.
2010 Csonka D. Investigation of pregnancy induced adrenergic denervation in the rat University of Szeged, Faculty of Pharmacy, Department of Pharmacodynamics and Biopharmacy
2011 Kocic I, Dworakowska D, Dworakowski R, Petrusewicz J. CGP 41251, a new potential anticancer drug, improves contractility of rat isolated cardiac muscle subjected to hypoxia J Cardiovasc Pharmacol. 2001 Jun;37(6):734-41.
2012 Raducu Popescu I, Bild W, Ciobica A, Bild V. Different modulatory effects of ammonium ions on angiotensin vascular actions in isolated rat aortic and renal arteries Arch. Biol. Sci., Belgrade, 64 (2), 427-433, 2012
2013 Jost N, Nagy N, Corici C, Kohajda Z, Horváth A, Acsai K, Biliczki P, Levijoki J, Pollesello P, Koskelainen T, Otsomaa L, Tóth A, Papp JG, Varró A, Virág L. ORM-10103, a novel specific inhibitor of the Na+/Ca2+ exchanger, decreases early and delayed afterdepolarizations in the canine heart Br J Pharmacol. 2013 Oct;170(4):768-78. doi: 10.1111/bph.12228.
2014 Sarika Singh,Sharad Sharma, C. Nath, Srikant Kumar Rath, R. K. Singh, Smrati Bhadauria, Poonam Singh, R.k. Shukla, Manoj Barthwal, M Dikshit Essential safety pharmacology and safety evaluation of bioactive fraction of Xylocarpus moluccensis an antidyslipidaemic agent  International journal of medical science and clinical Invention Volume 1 Issue 1 2014 page no. 24-47

Note: experiments were performed with different types of stimulators.


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