The zebra fish (Danio rerio) examination systems of the MDE GmbH are supporting the methodological back-ground of the physiological, pharmacological and toxicological researches in the fields of cardiovascular function and group behavior, on the highest measurement technical and data processing level possible.
It provides an opportunity to examine heart function of the adult zebra fish. The system can be effectively used to examine the effects and side-effects of candidate medicine molecules in pharmacology, safety pharmacology and toxicology.
Apart from the zebrfish's intensively popular cardiovascular usage, this species can also be efficiently used for neural and psycho-physiological/pharmacological basic- and applied researches. Examination and experimental influencing of neurotransmitter release is essential for studying information transfer between nerve cells and neural regulation of other organs.
The workstation specially designed for the standard microelectrode technique was further developed for measurement of the summed voltage response (AP) of ion channels of the embryonic and adult zebrafish heart.