Zebrafish systems
The zebra fish (Danio rerio) examination systems of the MDE GmbH are supporting the methodological back-ground of the physiological, pharmacological and toxicological researches in the fields of cardiovascular function and group behavior, on the highest measurement technical and data processing level possible.
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It provides an opportunity to examine heart function of the adult zebra fish. The system can be effectively used to examine the effects and side-effects of candidate medicine molecules in pharmacology, safety pharmacology and toxicology. |
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Apart from the zebrfish's intensively popular cardiovascular usage, this species can also be efficiently used for neural and psycho-physiological/pharmacological basic- and applied researches. Examination and experimental influencing of neurotransmitter release is essential for studying information transfer between nerve cells and neural regulation of other organs. |
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The workstation specially designed for the standard microelectrode technique was further developed for measurement of the summed voltage response (AP) of ion channels of the embryonic and adult zebrafish heart. |