Heart Cell Isolation setup 

MDE’s simplified isolated heart perfusion system is for efficient enzymatic digestion of heart cells in a controlled environment. Our system is manufactured with borosilicate glass, stainless steel framework, and laboratory-grade silicone tubing. This is a highly durable and reliable system, allowing researchers to reliably harvest cardiac cells for many years. Customized systems are also available […]

Classical Langendorff Type Heart Perfusion setup 

MDE’s first research instrument, a modernized version of the Classical Langendorff system, has been in production for over 40 years. It’s designed for retrograde perfusion of small rodent hearts and allows the use of one or two different buffer perfusions. Set up your Classical Langendorff and measure biopotentials, pressure, temperature, or flow. Our system includes […]

Working Heart Perfusion setup 

The Working Heart isolated heart perfusion technique involves the Neely-Langendorff method. The Working Heart method emphasizes maintaining physiological conditions during perfusion, enabling researchers to investigate aspects such as energy metabolism, oxygen consumption, and responses to different interventions, providing valuable insights into cardiac physiology and pathology. MDE has been manufacturing working heart systems for over 20 […]

Compact Langendorff setup

The compact, pump-controlled heart-perfusion system offered by MDE is a closed, integrated system designed for precise control and optimal performance in cardiovascular research. This system is housed within a water-circulation, self-heated fluid tank, providing a stable and isolated environment that eliminates the influence of ambient temperature fluctuations. The heart chamber is composed of borosilicate glass, […]