Isolated Heart Perfusion setups 

MDE offers four reliable types of isolated heart perfusion devices, providing economically feasible and flexible solutions for analyzing the extracorporeal circulation of small mammalian hearts in pharmacological and physiological research. Our systems are designed to accommodate a wide range of experiments, from simple digestion to complex working heart experiments. The key features of our isolated heart perfusion devices include:

  1. Sophisticated Designs: Our devices are meticulously designed to meet the specific needs of researchers conducting cardiac experiments. Whether it’s studying basic physiological processes or investigating pharmacological interventions, our systems offer the flexibility and reliability required for accurate data collection.
  2. Economic Feasibility: We understand the importance of cost-effectiveness in research settings. That’s why our isolated heart perfusion devices are engineered to provide high-quality results at an affordable price point, making them accessible to researchers with varying budgets.
  3. Versatility: Our systems are designed to accommodate a wide range of experimental settings, allowing researchers to tailor their experiments to their specific research questions. Whether it’s studying myocardial contractility, coronary flow, or ischemia-reperfusion injury, our devices offer the versatility needed to address diverse research needs.

Compact Langendorff setup

The compact, pump-controlled heart-perfusion system offered by MDE is a closed, integrated system designed for precise control and optimal performance in cardiovascular research. This system is housed within a water-circulation, self-heated fluid tank, providing a stable and isolated environment that eliminates the influence of ambient temperature fluctuations.

The compact, pump-controlled heart-perfusion system from MDE offers researchers a reliable and efficient platform for conducting cardiovascular research. Its innovative design, stable temperature control, and optimal heart-suspending unit make it an invaluable tool for studying cardiac function and physiology in laboratory settings.

Working Heart Perfusion setup 

The working heart isolated heart perfusion technique involves the Langendorff method. Working heart method emphasizes maintaining physiological conditions during perfusion, enabling researchers to investigate aspects such as energy metabolism, oxygen consumption, and responses to different interventions, providing valuable insights into cardiac physiology and pathology.

MDE has been manufacturing working heart systems for over 20 years, demonstrating our commitment to providing high-quality tools for cardiovascular research. Our systems are designed to meet the rigorous demands of scientific investigation, offering reliability, precision, and versatility to researchers worldwide. With MDE's working heart systems, researchers can conduct experiments with confidence, knowing they have access to advanced technology that enables groundbreaking discoveries in cardiac physiology and pathology.

Classical Langendorff Type Heart Perfusion setup 

MDE's first research instrument, a classical Langendorff system, remains relevant despite being over 40 years old. It's designed for retrograde perfusion of small rodent hearts and allows the use of one or two different buffer perfusions. Perfusion pressure is regulated by an inner glass tube, with buffer refill facilitated by a pump. The system includes taps for easy perfusion flow management, making it useful for teaching purposes. Despite its age, its versatility and precise regulation features continue to meet the needs of researchers.

Heart Cell Isolation setup 

MDE's simplified isolated heart perfusion system facilitates enzymatic digestion of heart cells in a controlled environment, allowing researchers to harvest cardiac cells for further investigation at the cellular level. Despite their simplicity, MDE offers state-of-the-art setups to streamline cell harvesting processes. 

Request User’s Manual

Please enter your name and email address and we will send you the user manual to your mailbox as soon as possible.