Isolated Heart Perfusion setups 

MDE offers four reliable types of isolated heart perfusion devices, providing economically feasible and flexible solutions for analyzing the extracorporeal circulation of small mammalian hearts in pharmacological and physiological research. Our systems are designed to accommodate a wide range of experiments, from simple digestion to complex working heart experiments. The key features of our isolated heart perfusion devices include:

  1. Sophisticated Designs: Our devices are meticulously designed to meet the specific needs of researchers conducting cardiac experiments. Whether it’s studying basic physiological processes or investigating pharmacological interventions, our systems offer the flexibility and reliability required for accurate data collection.
  2. Economic Feasibility: We understand the importance of cost-effectiveness in research settings. That’s why our isolated heart perfusion devices are engineered to provide high-quality results at an affordable price point, making them accessible to researchers with varying budgets.
  3. Versatility: Our systems are designed to accommodate a wide range of experimental settings, allowing researchers to tailor their experiments to their specific research questions. Whether it’s studying myocardial contractility, coronary flow, or ischemia-reperfusion injury, our devices offer the versatility needed to address diverse research needs.

Compact Langendorff setup

The compact, pump-controlled heart-perfusion system offered by MDE is a closed, integrated system designed for precise control and optimal performance in cardiovascular research. This system is housed within a water-circulation, self-heated fluid tank, providing a stable and isolated environment that eliminates the influence of ambient temperature fluctuations. The heart chamber is composed of borosilicate glass, and the tubing is laboratory-grade silicone tubing.

The compact, pump-controlled heart-perfusion system from MDE offers researchers a reliable and efficient platform for conducting cardiovascular research. Its innovative design, stable temperature control, and optimal heart-suspending unit make it an invaluable tool for studying cardiac function and physiology in laboratory settings.

Working Heart Perfusion setup 

The Working Heart isolated heart perfusion technique involves the Neely-Langendorff method. The Working Heart method emphasizes maintaining physiological conditions during perfusion, enabling researchers to investigate aspects such as energy metabolism, oxygen consumption, and responses to different interventions, providing valuable insights into cardiac physiology and pathology.

MDE has been manufacturing working heart systems for over 20 years, demonstrating our commitment to providing high-quality tools for cardiovascular research. Our systems are designed to meet the rigorous demands of scientific investigation. High quality borosilicate glass, with laboratory-grade tubing and fittings, mean we can offer reliability, precision, and versatility to researchers worldwide. Finally, with MDE's Working Heart systems, researchers can conduct both Working Heart and Classical Langendorff experiments, so you have a modern setup with excellent flexibility.

Classical Langendorff Type Heart Perfusion setup 

MDE's first research instrument, a modernized version of the Classical Langendorff system, has been in production for over 40 years. It's designed for retrograde perfusion of small rodent hearts and allows the use of one or two different buffer perfusions. Set up your Classical Langendorff and measure biopotentials, pressure, temperature, or flow.

Our system includes borosilicate glassware, laboratory-grade silicone tubing, and stainless steel framework, for maximum durability. Designed for easy perfusate flow management, maximum versatility, and precise regulation, our Classical Langendorff continues to meet the needs of researchers worldwide.
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Heart Cell Isolation setup 

MDE's simplified isolated heart perfusion system is for efficient enzymatic digestion of heart cells in a controlled environment. Our system is manufactured with borosilicate glass, stainless steel framework, and laboratory-grade silicone tubing. This is a highly durable and reliable system, allowing researchers to reliably harvest cardiac cells for many years. Customized systems are also available - contact us for more information and a quotation.

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