FAQ
MDE CardiScan
MDE CardiScan is used for comprehensive, non-invasive cardiovascular screening. It helps assess heart rate variability, autonomic nervous system function, and early signs of cardiac disease, especially in high-risk patients such as those with diabetes.
MDE CardiScan supports five automated Ewing reflex tests:
- Heart rate response to deep breathing
- Valsalva maneuver
- 30:15 ratio (heart rate change upon standing)
- Blood pressure drop upon standing
- Blood pressure rise during sustained handgrip
No. MDE CardiScan is designed for use by trained assistants or nurses. The system automates test execution and report generation, reducing reliance on specialists and freeing up clinical resources.
Depending on how many tests are selected, a session can take as little as 2 minutes or up to 21 minutes. This makes the system ideal for both quick screenings and detailed evaluations.
Yes. MDE CardiScan features a built-in comparison mode that allows practitioners to evaluate test results over multiple sessions. It’s ideal for monitoring disease progression or treatment efficacy.
Yes. MDE CardiScan features a built-in comparison mode that allows practitioners to evaluate test results over multiple sessions. It’s ideal for monitoring disease progression or treatment efficacy.
The system includes:
- Wireless, medical-grade ECG unit (3–12 lead)
- Non-invasive blood pressure measurement
- Wireless pressure sensor for Valsalva and handgrip tests
- Tablet with pre-installed software
- Disposable sterile Valsalva mouthpieces and a rubber grip ball
In addition to reflex responses, the system provides a full ECG evaluation:
- RR distance
- Heart rate (HR)
- ST, QT, QRS, and PR intervals
It also includes an HRV analysis module.
MDE CardiScan is particularly valuable in diabetes care, neurology, internal medicine, and sports cardiology. It can also be used in rehabilitation clinics and for general heart health check-ups.
Yes. The system meets CE and medical regulatory standards. It is intended for use in healthcare environments on adult patients, including those with certain physical limitations.
Yes. MDE CardiScan should not be used on patients with unstable cardiovascular conditions, recent strokes, aneurysms, electrical implants, or respiratory impairments. Patients must be cooperative and free from severe hypertension or arrhythmias before testing.
MDE SensoriScan
The NM-01/CPT MDE SensoriScan
is a neurological diagnostic device used for neuroselective sensory nerve screening through Current Perception Threshold (CPT) testing. It delivers early neuropathy detection by identifying functional impairment of sensory nerves – both large and small fibers – before symptoms become serious.
CPT stands for Current Perception Threshold. It measures the lowest electrical current a patient can feel at specific frequencies, each targeting a different nerve fiber type (Aβ, Aδ, or C). The result indicates nerve sensitivity and integrity.
Not at all. The non-invasive nerve test is completely painless. Patients feel only a light tingling or vibration, with no needles or discomfort.
Each test takes just a few minutes per site. Multiple areas (toes, fingers, lower limbs, etc.) can be tested during one session.
Unlike standard nerve conduction studies (which often require needles or electrodes to stimulate motor nerves), the MDE SensoriScan
specifically targets sensory nerves and measures perception, not muscle response. It also differentiates fiber types, which most traditional tests cannot.
It’s effective in diagnosing or monitoring:
- Diabetic peripheral neuropathy
- Carpal tunnel syndrome
- Kidney disease-related nerve damage
- Pelvic pain disorders
- Early neurodegeneration (Alzheimer’s, post-COVID, etc.)
Yes. Since it delivers consistent, quantifiable CPT scores, the Neurometer is ideal for tracking nerve function over time and evaluating how well treatments are working.
Absolutely. More than 800 peer-reviewed studies support its sensitivity and specificity. MDE has also validated the technology in controlled patient groups, confirming accuracy across diverse populations.
No. The MDE SensoriScan
is low-maintenance, reliable, and does not require frequent calibration or annual inspections, making it ideal for routine clinical use.
The MDE SensoriScan
is especially useful for:
- People with diabetes or metabolic syndrome
- Patients with chronic pain or unexplained numbness
- Individuals at risk of neurological complications due to other chronic diseases or post-viral syndromes
- Clinics and practices needing a fast, non-invasive nerve screening tool
GastroGuard-beta
It offers a painless way to monitor gastrointestinal motility, helping diagnose disorders like gastroparesis, reflux disease, and ileus without endoscopy or manometry.
Surface electrodes record smooth-muscle electromyography; proprietary algorithms turn raw voltages into motility indices for each gut segment.
They capture muscle rhythm directly, work anywhere, and avoid the discomfort and infection risk of intraluminal catheters.
Yes. By correlating meals with motility peaks and troughs, users learn ideal eating windows and identify ingredients that slow digestion.
No. Athletes, wellness enthusiasts, and researchers use GastroGuard for routine digestive system monitoring and diet optimization.
It combines multi-segment SEMG, motion-artifact suppression, and cloud analytics in a lightweight belt, something no traditional EGG system offers.
MDE Technologies is adding AI-driven anomaly alerts and expanding the sensor suite to include temperature and stress-related heart-rate variability.
Amplifiers & Stimulators
Force, pressure, temperature, standard ECG, and nine-lead ECG—all with analog outputs and fixed calibration signals.
They inject known voltages or pressures, letting you zero and scale any DAQ channel in seconds—no external calibrator required.
Choose 1-, 2-, 3-, or 4-channel housings; multiplex ECG offers nine synchronous inputs.
Yes. Standard 6.3 mm jack or D-Sub outputs (100 Ω) connect to virtually any scientific measurement device.
Isolated models cap output at 2.5 W and ±50 V for added operator and specimen safety; non-isolated units reach 10 W and ±100 V for higher-energy protocols.
Absolutely. High input impedance (10 MΩ) and switchable 3 / 10 / 40 Hz filters minimize baseline drift and mains noise.
Yes - interchangeable patient cables support mouse, rat, dog, pig, and more. Custom leads are available on request.
±0.1 °C across the 20–50 °C range, with LED readout and 10 mV / °C analog output.
We can package amplifiers, stimulators, transducers, electrodes, and software as a turnkey in-vitro equipment bundle—just tell us your protocol.
Short-circuit protection, input diode clamping, and selectable isolation keep both operator and specimen safe during high-voltage or high-current work.
Gill-Perfusion Solution
It pumps oxygen-rich buffers across the gills, keeping adult zebrafish anesthetized yet fully perfused. This stabilizes ECG baselines and allows compound delivery without systemic injections.
Silver-chloride micro-electrodes contact the body surface; proprietary filtering removes motion noise, yielding crisp ECG traces comparable to mammalian tele-ECG.
Heart rate, rhythm, conduction velocity, QT prolongation, drug-induced arrhythmia, ischemia–reperfusion response, and regenerative recovery after injury.
They regrow functional myocardium within weeks, offering a living blueprint for human regenerative therapies.
Yes. The perfusion medium can be stepped or continuously infused with test articles, enabling fine-grained PK-PD profiling.
No. Pre-configured flow rates, disposable perfusion lines, and intuitive software mean one trained technician can manage multiple assays in a single session.
Labs routinely process 8–12 fish per day on one unit, scaling higher with parallel systems.
Early zebrafish ECG data de-risks pipelines by revealing cardiotoxic liabilities, reducing late-stage failures, and animal usage downstream.
Absolutely. Data export options include CSV and EDF, ready for most laboratory information platforms.
Isolated Heart Perfusion Setups
These systems allow researchers to study heart function outside the body under controlled conditions. Applications include studying contractility, coronary flow, ischemia, reperfusion, metabolism, and electrophysiology.
The Classical Langendorff system uses retrograde perfusion to keep the heart beating without generating pressure. The Working Heart system simulates more natural, forward-flow conditions, enabling measurements of pressure, cardiac output, and oxygen use.
It offers a compact, closed-loop design with integrated heating and temperature control. This setup is ideal for researchers who need stability, precision, and a minimal footprint for rodent heart studies.
Yes. MDE’s Working Heart system allows you to alternate between Working Heart and Classical Langendorff modes, maximizing experimental flexibility.
Every unit is built with medical-grade glass, silicone, and stainless steel, ensuring long-term durability and chemical resistance. Our systems are also designed for easy maintenance and consistent performance over years of research use.
They allow researchers to apply pharmacological compounds in real time and monitor their effects on cardiac function, including changes in contractility, heart rate, and coronary flow.
It’s used for the enzymatic digestion of cardiac tissue, allowing researchers to extract viable heart cells for downstream applications, such as patch-clamp analysis, flow cytometry, or regenerative studies.
Yes. MDE perfusion setups are used in both academic and commercial labs, offering simple operation and robust construction, which makes them perfect for both student training and high-level research.
Absolutely. We provide technical guidance, user manuals, and offer custom configurations upon request. Contact us for a quote or to discuss a tailored system consultation.
Isolated Nerve Tissue Perfusion Setup
It’s a lab system designed for in vitro analysis of nerve tissue. It allows researchers to observe neurotransmitter release, nerve excitability, and synaptic response under carefully controlled conditions.
Superfusion keeps the tissue oxygenated and chemically stable while allowing researchers to apply and wash off compounds precisely, preserving the natural environment of the sample.
What kind of stimulation can be applied?
You can apply:
- Electrical field stimulation via integrated platinum electrodes
- Chemical stimulation via dissolved compounds in the perfusate or direct application
- Radiolabeled substance stimulation for quantitative release tracking
A double-walled incubator, controlled perfusion temperature, and carbogen gas bubbling ensure that tissues remain viable for extended experimental sessions.
Yes. The system supports combined stimulation protocols, letting researchers explore compound interactions with neural excitability and synaptic transmission.
It’s ideal for:
- Neurotransmitter release studies
- Synaptic transmission and receptor response
- Neuromodulation and pharmacological screening
- Neuroinflammation and disease models
Localized delivery improves accuracy by minimizing effects on non-target areas and allows for fine-tuned targeting of neural circuits or tissue zones.
Yes. MDE offers adaptable chamber designs and accessory options to suit different species, tissue types, and experimental protocols.
The superfusion technique, paired with robust stimulation controls and gas exchange, ensures high reproducibility and consistent conditions across trials.
We offer technical assistance, manuals, and custom guidance on experiment setup — ensuring researchers can get up and running quickly and confidently.
Isolated Tissue Bath Setups
It’s a lab apparatus that allows researchers to study the functional response of isolated tissue samples, such as smooth muscle, when exposed to various conditions, including drugs or electrical stimuli.
You can test smooth muscle and vascular tissues from a range of organs: the ileum, colon, trachea, bladder, vas deferens, aortic rings, corpus cavernosum, and more.
Our systems use carbogen bubbling through ultrafine frits, combined with temperature-controlled chambers and perfusate solutions like Krebs-Henseleit or Tyrode’s, to maintain a stable, oxygenated environment.
They’re chemically resistant, easy to clean, and designed to hold tissue samples firmly but gently. Mounting can be done outside the chamber, simplifying setup.
Standard volumes include 5 ml, 10 ml, and 20 ml. You can also adjust the volume by changing the immersion depth or request custom chambers for unique experimental setups.
Yes. We offer multi-channel systems (1, 2, 4, or 8 chambers) — each with its own reservoir, allowing you to test multiple tissues under different conditions simultaneously.
Stable oxygenation ensures tissue viability and consistent physiological responses. Our dual-input bubbling system allows more granular control of oxygen levels, enhancing data accuracy.
Quick replacement with standard silicone tubing reduces downtime and contamination risk, and eliminates the need for expensive proprietary parts.
All components — from borosilicate glass chambers to stainless steel framework — are built for long-term use in high-throughput labs.
Our isolated tissue bath setups are used globally in university research labs, pharmaceutical companies, and government-funded biomedical research programs across Europe, the U.S., India, and beyond.
Liver & Kidney Perfusion Setups
It maintains excised organs under near-physiological conditions to study drug clearance, toxicant effects, vascular reactivity, and graft viability without whole-animal variability.
Isolation removes confounding systemic factors, lets you fine-tune perfusate composition, and yields cleaner PK/PD data—accelerating drug metabolism research and reducing animal numbers.
Inline transducers stream to the software; the pump auto-adjusts flow or stops if pressure drifts, protecting delicate sinusoidal and glomerular networks.
Yes. Twin-loop kits allow parallel perfusion with independent flow and sampling, ideal for comparing hepatic and renal metabolism of the same compound.
Absolutely. A flat bed prevents ureter kinking, maintains even perfusion, and enables straightforward urine collection for organ function testing.
Built-in temperature ramps and oxygen control let you simulate cold storage, controlled re-warming, and reperfusion, critical steps in transplantation research.
Dedicated outlets feed chilled vials; low circuit volume means higher analyte concentration and easier downstream quantification.
Continuous heparinized buffer, smooth-bore tubing, and pulsation-free flow reduce shear stress and clot risk, keeping perfusions stable for 4-6 hours.
Its non-immersive horizontal chamber, micro-volume circuit, and plug-and-play sensor suite deliver unmatched stability, sample economy, and data fidelity, raising the bar for isolated organ study in Europe and beyond.
Small Vessel Myograph Setups
It’s a precision tool used to conduct pharmacological vessel study. By mounting vessel rings under isometric conditions, researchers can monitor how vessels respond to various compounds or stimuli.
Any small vessel with an internal diameter between 60 μm and 10 mm, including arterioles, small arteries, and venous rings from humans or animal models.
Once mounted, the vessel's diameter is fixed, and changes in contractile force are measured in real-time. This allows for an accurate assessment of how vessels contract or relax in response to specific substances.
Our water-circulated heating maintains a stable 37°C environment more efficiently than electrical systems. It improves thermal uniformity, minimizes signal noise, and supports long-duration experiments.
Yes. The system supports both baseline physiological studies and detailed pharmacological screenings. You can introduce agonists, antagonists, or test novel compounds.
- Isometric contractile force
- Dose-response relationships
- Time-dependent vessel behavior
- Cross-comparisons between tissues
Vessels are dissected, cleaned, and mounted as ring segments on fine wires. Our mounting supports ensure gentle tensioning without damaging the vessel wall.
Stable temperature is critical for replicating in vivo conditions. Inconsistent heat can alter vessel responsiveness or compromise tissue viability, which is why our water-based system offers superior thermal stability.
Yes. While our systems come with Isosys data acquisition, they’re fully compatible with third-party DAQ platforms, allowing seamless integration into your current setup.
Our myographs are used in academic labs, pharmaceutical R&D, and cardiovascular research centers across Europe and North America. They’re trusted for both teaching and advanced vascular studies.